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BRIEF: Could you help me find a website on the critical effects and target organs for non-carcinogens?


QUESTION:
Can anyone direct me towards a source (hopefully on the net) which identifies the critical effects and target organs for s. I have gleaned what I can from the IRIS database, but need more information for a risk assessment (i.e., segregation of hazard indices).

ANSWER:

The EDF Chemical Scorecard provides lists of chemicals that have been associated with various noncancer health effects by a variety of published sources, with full references to the source making the hazard identification. See http://www.scorecard.org/health-effects/ if you want a list of chemicals by endpoint See http://www.scorecard.org/chemical-profiles/ if you want to search for endpoints for a specific chemical If your specific interest is defining the set of chemicals that should be considered for estimating a cummulative hazard index for a specific noncancer health effect, the best guidance I am aware of has been developed by CalEPA: CalEPA, Office of Environmental Health Hazard Assessment. Draft Technical Support Document for the Determination of Noncancer Chronic Reference Exposure Levels (10/97)